The 24th Michigan Infantry was organized at Detroit, Michigan and mustered into Federal service on August 15, 1862. It was assigned to the famous Iron Brigade in the Army of the Potomac. The brigade's commander General John Gibbon had requested a new regiment be added to his command because its four original regiments (the 2nd, 6th, and 7th Wisconsin and the 19th Indiana) had been severely depleted by combat action and numbered less than 1000 men total by October 1862. He said that ideally it should be a Western regiment since the others were from that part of the country. Gibbon's request granted, the 24th Michigan joined the brigade and saw its first action at Fredericksburg taking on a nuisance battery of Confederate horse artillery south of the town.
The regiment was selected as escort at funeral of President Abraham Lincoln.